FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to pharmaceutical coformulated preparative forms containing calcium channel blocker on the basis of dihydropyridine, such as amlodipine and ARB (angiotensin-2 receptor blocker), such as losartan.
EFFECT: group of inventions refers to chronotherapeutic coformulated preparative forms for preventing and treating cardiovascular diseases on the basis of xenobiotics and chronotherapy for providing chronotherapeutic release of two therapeutic agents hereby enhancing therapeutic activity as compared with the combined introduction of each therapeutic agent in the form of an individual pill, simultaneously reducing side effects and maintaining such high therapeutic activity as possible for a certain period of time a day when a risk of cardiovascular complications is highest.
20 cl, 11 dwg, 7 tbl, 30 ex
| Title | Year | Author | Number |
|---|---|---|---|
| COMBINED CONTROLLED-RELEASE PHARMACEUTICAL AGENT CONTAINING DIHYDROPYRIDINE CALCIUM CANAL BLOCKERS AND HMG-CoA-REDUCTASE INHIBITORS | 2007 |
|
RU2450804C2 |
| COMBINATION OF ORGANIC COMPOUNDS | 2003 |
|
RU2324482C2 |
| MEDICINAL AGENT FOR TREATMENT OF HYPERTENSION OR HIGH BLOOD PRESSURE | 2010 |
|
RU2539382C2 |
| METHOD OF TREATING CARDIOVASCULAR DISEASES | 2012 |
|
RU2570752C2 |
| CONTROLLED RELEASE COMPLEX PHARMACEUTICAL COMPOSITION CONTAINING ANGIOTENSIN-II RECEPTOR BLOCKERS AND HYDROXIMETHYLGLUTARYL-COA REDUCTASE INHIBITORS | 2007 |
|
RU2453307C2 |
| COMPOSITION INCLUDING AMLODIPINE AND LOSARTAN HAVING IMPROVED STABILITY | 2013 |
|
RU2628538C2 |
| STABLE PHARMACEUTICAL PREPARATION CONTAINING AMLODIPINE BENZYLATE AND ATENOLOL | 1998 |
|
RU2188636C2 |
| COMBINATION OF DIPEPTIDILPEPTIDASE IV (DPP IV) INHIBITOR AND CARDIOVASCULAR SUBSTANCE | 2003 |
|
RU2336876C2 |
| PHARMACEUTICAL COMPOSITION INCLUDING RENIN INHIBITOR, CALCIUM CHANNEL BLOCKER AND DIURETIC | 2003 |
|
RU2316318C2 |
| NEBIVOLOL-INCLUDING COMPOSITIONS | 2005 |
|
RU2403037C2 |
