METHOD OF TREATING DIFFUSE MYOCARDIAL DAMAGE Russian patent published in 2012 - IPC A61M5/00 A61K35/28 A61P41/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, specifically cardiology and cardiosurgery, and may be used for treating diffuse myocardial damage. That is ensured by cell sampling of mononuclear fraction of bone marrow in number of 10 mln cells. The 5 mln cells are introduced by aortic puncture between a coronary artery mouth and a short-term clamping point in an ascending section to a junction to a common carotid artery. The rest 5 mln cells are introduced by two injections. The first 2.5 mln cells are introduced in an apex of the left ventricular myocardium, while the second 2.5 mln cells are introduced into a side wall of the left ventricular myocardium.

EFFECT: method provides functional recovery of the damaged myocardium ensured by the enlarged area of the microvasculature in an ischemic segment of muscular tissue due to formation of local permanent loci of angiogenesis ensured by maximum cell accumulation for the first hour after transplantation and minimum escape from the myocardium for the first 20 hours after the combined introduction.

3 tbl