PYRIMIDYL INDOLINE COMPOUND Russian patent published in 2012 - IPC C07D401/14 A61K31/506 A61P3/04 A61P3/10 

FIELD: chemistry.

SUBSTANCE: in general formula (I) p equals 1 or 2; R¹ is methyl, ethyl, propyl, isobutyl, 2-fluoroethyl or cyclobutyl; m equals 0; each R² is absent; n equals 0; each R³ is absent; R⁴ is a hydrogen atom; R⁵ is a hydrogen atom; R⁶ is -C(O)O-R^6a; R^6a is a C₁-C₆alkyl group which can have 1-3 substitutes selected from a group of substitutes α, where the group of substitutes α is a group consisting of a halogen atom, a hydroxyl group, a C₁-C₆alkoxy group, a C₃-C₇cycloalkyl group, an amino group, a mono- or di(C₁-C₆alkyl)amino group, a phenyl group, and a furyl group; and R⁷ is a hydrogen atom.

EFFECT: compounds have the property of reducing the blood glucose level and can be used to treat and/or prevent type 1 sugar diabetes, type 2 sugar diabetes or diabetes-associated diseases caused by low glucose tolerance, as well as to prevent obesity caused by low glucose tolerance.

11 cl, 2 tbl, 119 ex