METHOD OF DETERMINING STABILITY OF COSMETIC PRODUCT EMULSION Russian patent published in 2012 - IPC A61K8/06 

Abstract RU 2464970 C1

FIELD: medicine.

SUBSTANCE: invention relates to chemical-pharmaceutical industry and represents method of determining cosmetic product emulsion stability, characterised by the following: selection and preparation of samples are carried out and centrifuged and it differs by the fact that at the first stage carried out are microscopic observation of centrifuged material and calculation of number of micelle n on site 1 cm2 at 10, or 40, or 100-multiple magnification with the following comparison with the number of micelles n0 in sample, which is not subjected to preparation, considering emulsion conditionally stable at and at the second stage samples with conditionally stable emulsion, are subjected by accelerated aging during a month by placing of examined samples in thermostat and keeping at temperature 40-42°C and relative humidity 65±2%, periodically carrying out microscopic observation of samples on 1 cm2 site at 10, or 40, or 100-multiple magnification and statistic processing of experimental data with construction of mathematical model of forecast and solution of equation of form where n' - is number of micelles, pieces./cm2; τ is time of accelerated aging, days; design factors of exponential equation, obtained in processing experimental data, at τ → given time of storing, with calculation of possible emulsion state, in case of value emulsion is considered stable and suitable for durative storage, and in case of it is considered unsuitable for durative storing.

EFFECT: invention ensures increased effectiveness of determination of emulsion stability.

2 ex, 2 tbl, 6 dwg

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RU 2 464 970 C1

Authors

Germanova Anastasija Viktorovna

Tarasov Vasilij Evgen'Evich

Dates

2012-10-27Published

2011-07-06Filed