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2 467 334

(13)

(51)

IPC

G01N33/53(2006-01-01)

(21) (22)

Application

2010135468/15, 2010-08-24

(24)

Start date

2010-08-24

(22)

Actual filing date

2010-08-24

(45)

Published

2012-11-20

(72)

Inventor

Lutsenko Mikhail TimofeevichIshutina Natalija Aleksandrovna

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Uchrezhdenie Nauchnyj Tsentr Fiziologii I Patologii Dykhanija" Sibirskogo Otdelenija Ramn

METHOD FOR ASSESSING ERYTHROCYTE MEMBRANE MICROVISCOSITY BY CALCULATING PYRENE EXIMERISATION COEFFICIENT C IN PREGNANT WOMEN SUFFERED AGGRAVATED HERPES VIRAL INFECTION IN THIRD TRIMESTER OF PREGNANCY WITH REGARD TO EVALUATION OF PERCENTAGE OF OLEIC ACID IN ERYTHROCYTE MEMBRANES Russian patent published in 2012 - IPC G01N33/53

Abstract RU 2467334 C2

FIELD: medicine.

SUBSTANCE: invention is applied for assessing erythrocyte membrane microviscosity. The presented method involves calculating a pyrene eximerisation coefficient C_ex in pregnant women suffered aggravated herpes viral infection in the third trimester of gestation. Additionally, the content of oleic acid in erythrocyte membranes is evaluated. If antibody titre 1:12800 is accompanied by the decreased content of oleic acid to 16.52±0.14%; decreased C_ex in a lipid bilayer to 0.60±0.005; C_ex in protein-lipid contacts to 0.79±0.004, higher erythrocyte membrane microviscosity is assessed.

EFFECT: provided assessment of erythrocyte membrane microviscosity.

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RU 2 467 334 C2

Authors

Lutsenko Mikhail Timofeevich

Ishutina Natalija Aleksandrovna

Dates

2012-11-20—Published

2010-08-24—Filed