AMINE SALTS OF CRTH2 ANTAGONIST Russian patent published in 2012 - IPC C07D239/48 A61K31/505 A61P1/00 A61P11/06 A61P17/06 A61P27/14 A61P37/08 

Abstract RU 2468013 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to method of obtaining said salts, to pharmaceutical composition, containing said salts, and to application of salt for preparation of medication for treatment, prevention or relief of one or several symptoms of disease, mediated by CRTH2, associated with eosinophils, basophils, where disease is selected from asthma, allergic asthma, asthma of physical effort, allergic rhinitis, atopic dermatitis, contact hypersensitivity and hyper IgE syndrome.

EFFECT: invention relates to novel pharmaceutically acceptable salts, containing pharmaceutically acceptable amine, selected from ethylenediamine, piperazine, benzathine or choline and {4,6-bis(dimethylamino)-2-(4-(4-(trifluoromethyl)benzamido)benzyl)pyrimidin-5yl}acetic acid.

43 cl, 21 dwg, 4 tbl, 6 ex

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RU 2 468 013 C2

Authors

Laj Taj Vehj

Dates

2012-11-27Published

2008-06-18Filed