CRTH2 ANTAGONIST PARTICLES Russian patent published in 2012 - IPC C07D239/48 A61K31/505 A61P1/00 A61P11/06 A61P17/06 A61P27/14 A61P37/08 

Abstract RU 2468012 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to novel crystalline forms I, II and amorphous form of {4,6-bis(dimethylamino)-2-(4-(4-(trifluoromethyl)benzamido)benzyl)pyrimidin-5-yl}acetic acid.

EFFECT: invention relates to pharmaceutical composition, containing crystalline form I of compound and to application of crystalline form I for treatment, prevention or relief of one or more symptoms of disease, mediated by CRTH2, associated with eosinophils, basophils, where disease is selected from asthma, allergic asthma, asthma, induced by physical effort, allergic rhinitis, perennial allergic rhinitis, seasonal allergic rhinitis, atopic dermatitis, contact hypersensitivity.

16 cl, 11 dwg, 8 tbl,11 ex

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RU 2 468 012 C2

Authors

Laj Taj Vehj

Li Khoj-In'

Dates

2012-11-27Published

2008-06-18Filed