DERIVATIVES OF IMIDAZO[1,2-C]PYRIMIDINYL ACETIC ACID Russian patent published in 2009 - IPC C07D487/04 A61K31/519 A61P1/04 A61P11/02 A61P11/06 A61P17/04 A61P17/06 A61P19/02 A61P27/02 A61P27/14 A61P29/00 A61P35/02 A61P37/08 

FIELD: chemistry.

SUBSTANCE: invention relates to new derivatives of imidazo[1,2-c]pyrimidinyl acetic acid of formula (I) or to its salts: , where R¹ is ,, in which n is an integer ranging from 0 to 6; Y is aryl, where the said aryl is optionally substituted at a substitutable position with one or more substitutes selected from a group which consists of halogen or C_1-6alkyl, optionally substituted with mono-, di- or trihalogen; R² is hydrogen; R³ is hydrogen or halogen; and R⁴ is hydrogen. The invention also relates to derivatives of imidazo[1,2-c]pyrimidinyl acetic acid of formula (I-i) or to its salts, to a drug, to use of compounds in paragraph 1, as well as to a drug in form of a standard single dosage.

EFFECT: obtaining new biologically active compounds, which are active towards CRTH2.

23 cl, 2 ex