FIELD: medicine.
SUBSTANCE: invention relates to field of biotechnology, namely to method of estimating efficiency of therapy of urinary bladder cancer in humans by method of immunofermentative analysis. Claimed invention can be used in medicine. Method includes obtaining samples of patient's urine and/or blood. Mixtures of protein components of urine and blood are separated. Performed is reaction of immunofermentative analysis with monoclonal and/or polyclonal antibodies against recombinant protein UBE2C and/or its unique fragments longer than 8 amino acids. Therapy efficiency is determined by determination of UBE2C protein content in analysed samples, conclusion about performed therapy efficiency is made on 2 and more-fold reduction of level of UBE2C protein in urine and/or blood after performed therapy in comparison with initial level of said protein in urine and/or blood, determined before beginning of treatment.
EFFECT: invention makes it possible to diagnose urinary bladder cancer, including at the early stage of tumour transformation progress, with high reliability.
4 dwg, 4 tbl, 5 ex
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