METHOD OF DIAGNOSING CLEAR CELL RENAL CELL CARCINOMA AND SET FOR ITS REALISATION Russian patent published in 2015 - IPC G01N33/68 G01N33/574 

Abstract RU 2545998 C2

FIELD: medicine.

SUBSTANCE: claimed group of inventions relates to the field of medicine, in particular to oncology and molecular biology. Claimed are a method and a set of primers and a probe with sequences SEQ ID NO: 1, 2 and 3 for the realisation of a polymerase chain reaction in a real time mode to diagnose clear cell renal cell carcinoma (CCRCC). The quantitative content of mRNA of the NETO2 gene is evaluated. In case of an increased content of mRNA in a supposedly cancer-affected human tissue in comparison with the quantity of mRNA in a healthy tissue, CCRCC is diagnosed.

EFFECT: claimed group of inventions makes it possible to diagnose CCRCC with high reliability, including an early stage of the tumour disease.

4 cl, 1 dwg, 5 tbl, 6 ex

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RU 2 545 998 C2

Authors

Kudrjavtseva Anna Viktorovna

Kondrat'Eva Tat'Jana Tikhonovna

Dmitriev Aleksej Aleksandrovich

Mel'Nikova Natalija Vladimirovna

Senchenko Vera Nikolaevna

Oparina Nina Jur'Evna

Speranskaja Anna Sergeevna

Sadritdinova Asija Fajazovna

Snezhkina Anastasija Vladimirovna

Darij Marija Valer'Evna

Uroshlev Leonid Andreevich

Stepanov Oleg Alekseevich

Lakunina Valentina Aleksandrovna

Dates

2015-04-10Published

2012-09-27Filed