FIELD: medicine.
SUBSTANCE: claimed group of inventions relates to the field of medicine, in particular to oncology and molecular biology. Claimed are a method and a set of primers and a probe with sequences SEQ ID NO: 1, 2 and 3 for the realisation of a polymerase chain reaction in a real time mode to diagnose clear cell renal cell carcinoma (CCRCC). The quantitative content of mRNA of the ACY1 gene is evaluated. In case of a reduced content of mRNA in a supposedly cancer-affected human tissue in comparison with the quantity of mRNA in a healthy tissue, CCRCC is diagnosed.
EFFECT: claimed group of inventions makes it possible to diagnose CCRCC with high reliability, including an early stage of the tumour disease.
4 cl, 1 dwg, 5 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF DIAGNOSING CLEAR CELL RENAL CELL CARCINOMA AND SET FOR ITS REALISATION | 2012 |
|
RU2545998C2 |
| DIAGNOSTIC TECHNIQUE FOR CLEAR CELL RENAL ADENOCARCINOMA AND SET FOR IMPLEMENTATION THEREOF | 2009 |
|
RU2393472C1 |
| DIAGNOSTIC TECHNIQUE FOR PAPILLARY CELL RENAL CARCINOMA AND SET FOR IMPLEMENTATION THEREOF | 2014 |
|
RU2605829C2 |
| DIAGNOSTIC METHOD OF RENAL CELL CARCINONMA | 2016 |
|
RU2643586C1 |
| DETERMINING mRNA LEVEL REDUCTION IN GENES ITGA9, HYAL1 AND HYAL2 AS METHOD OF DIAGNOSING NON-SMALL CELL LUNG CANCER AND SET FOR ITS REALISATION | 2008 |
|
RU2403575C2 |
| METHOD OF DIAGNOSING SQUAMOUS CELL CARCINOMA OF LUNG AND KIT FOR IMPLEMENTATION THEREOF | 2014 |
|
RU2586779C2 |
| DIAGNOSTIC TECHNIQUE FOR NON-SMALL CELL CARCINOMA OF LUNG AND KIT FOR IMPLEMENTATION THEREOF | 2008 |
|
RU2390780C1 |
| SET OF REAGENTS FOR DETERMINING THE RISK OF RECURRENCE OF BREAST CANCER | 2017 |
|
RU2671557C1 |
| METHOD OF DIAGNOSING NON-SMALL CELL LUNG CANCER AND SET FOR REALISING IT | 2007 |
|
RU2351936C1 |
| DIAGNOSTIC TECHNIQUE FOR BLADDER CANCER (VERSIONS) AND KIT FOR IMPLEMENTATION THEREOF | 2011 |
|
RU2469323C2 |
