PHARMACEUTICAL COMPOSITION FOR TRANSDERMAL APPLICATION FOR INCREASE OF DRUG ACTIVITY AND DECREASE OF SIDE EFFECTS Russian patent published in 2012 - IPC A61K9/107 A61K9/127 A61K9/06 A61K31/00 

Abstract RU 2469706 C2

FIELD: medicine.

SUBSTANCE: phospholipid emulsion contains lecithin with the phosphatidylcholine content min. 60%, ethanol, water and diclofenac sodium in the amounts specified in the patent claim. The phospholipid emulsion represents liposomes (nanosomes) of a mean diameter of 20 to 500 nm. The composition is used for the liposomal introduction of biologically active substances and/or drugs into a human body. The emulsion nanosomes may additionally contain one or more substances specified in a group: carotinoids, flavonoids, vitamins, resveratrol, vitamin-like substances, cartilage protectors, amino acids, preserving agents.

EFFECT: emulsion provides selectivity of the effect of the active compound on body tissues, enables adjusting skin penetration rate of the active substance, dosing the active ingredients, increasing bioavailability of the active substances, reducing their negative effect of the body.

13 cl, 7 dwg, 1 tbl, 11 ex

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RU 2 469 706 C2

Authors

Manerov Jurij Vasil'Evich

Sotnikova Elena Mikhajlovna

Egorov Aleksej Glebovich

Dates

2012-12-20Published

2010-01-29Filed