FIELD: pharmacology.
SUBSTANCE: capsules for oral use comprise liposomes prepared by mixing egg lecithin, PEG 2000 and Tween-80 at the ratio of 6:2:1 at a temperature of 40°C, followed by hydration, encapsulated for oral use, wherein liposomes comprise isoniazid as an active agent in the following ratio of liposome components, g per 1 capsule: isoniazid - 0.3; a mixture of phospholipid, PEG 2000 and Tween-80 - 0.22. Number 0 capsules with a diameter of 7.65 mm, length of 21.7 mm, filling volume of 0.68 ml are additionally used.
EFFECT: agent has antiphthisic effect, as well as constant-rate release of active agents and pronounced prolonged action, it is convenient for using by patients themselves.
3 tbl, 3 ex
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Authors
Dates
2017-06-19—Published
2016-05-04—Filed