PIPERIDINE DERIVATIVE Russian patent published in 2012 - IPC C07D401/06 C07D401/14 C07D491/56 A61K31/404 A61P35/00 

FIELD: chemistry.

SUBSTANCE: invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof: (I) where R¹, R² and R³, which are identical or different, denote H, lower alkyl; R⁴, R⁵, R⁶, R⁷ and R⁸, which are identical or different, denote H, lower alkyl, halogen, nitro, -X-OR⁰, -X-NR¹⁰R¹¹, -X-NR⁰C(O)R¹⁰, -X-O-halogen lower alkyl, -X-O-X-phenyl; or R⁶ and R⁷ are combined to form -O-lower alkylene-O-; R, which is identical or different, denotes H, lower alkyl; R¹⁰, R¹¹, which are identical or different, denote H, lower alkyl; X, which is identical or different, denotes a bond, lower alkylene.

EFFECT: compounds exhibit type 5 17βHSD inhibiting activity, which enables their use in producing a pharmaceutical composition and in a method of inhibiting type 5 17βHSD.

15 cl, 11 tbl, 13 ex