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2 422 446

(13)

(51)

IPC

C07D491/107(2006-01-01)

C07D491/20(2006-01-01)

A61K31/438(2006-01-01)

A61P3/00(2006-01-01)

(21) (22)

Application

2008106243/04, 2006-07-14

(24)

Start date

2006-07-14

(22)

Actual filing date

2006-07-14

(45)

Published

2011-06-27

(72)

Inventor

Jamakava TakeruDzona KhidekiNiijama KendziJamada KodziIino TomokharuOkhkubo MitsuruImamura KhideakiKusunoki DzunJang Likhu

(73)

Holder

Merk Sharp Ehnd Domeh Korp.Baniu Farmas'Jutikal Ko., Ltd.

SPIROCHROMANONE DERIVATIVES AS ACETYL COENZYME A CARBOXYLASE (ACC) INHIBITORS Russian patent published in 2011 - IPC C07D491/107 C07D491/20 A61K31/438 A61P3/00

Abstract RU 2422446 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a compound of formula (I) or to its salt or ester in which radicals and symbols have the values presented in claim 1. These compounds are ACC inhibitors.

EFFECT: production of compounds to be applied as a therapeutic agent for various ACC-related disorders such as bacony liver, hyperlipidemia, obesity and diabetes.

13 cl, 48 ex

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RU 2 422 446 C2

Authors

Jamakava Takeru

Dzona Khideki

Niijama Kendzi

Jamada Kodzi

Iino Tomokharu

Okhkubo Mitsuru

Imamura Khideaki

Kusunoki Dzun

Jang Likhu

Dates

2011-06-27—Published

2006-07-14—Filed