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2 470 916

(13)

(51)

IPC

C07D207/325(2006-01-01)

C07D403/12(2006-01-01)

C07D405/10(2006-01-01)

C07D409/02(2006-01-01)

C07D417/02(2006-01-01)

A61K31/40(2006-01-01)

(21) (22)

Application

2007107388/04, 2005-07-30

(24)

Start date

2005-07-30

(22)

Actual filing date

2005-07-30

(45)

Published

2012-12-27

(72)

Inventor

Kanne Bannen LinnChen DzheffDehlrimpl Liza EhsterFlehtt Brenton T.Forsajt Timoti PatrikGu Sjao-KhojMehk Morrison B.Mann Larri U.Mann GrejsMartin RichardMokhan RadzhuMerfi BrehttNajman Majkl Charl'ZStivens Uill'Jam K. Ml.Van Te-Lin'Van JunVu Dzhejson Kh.

(73)

Holder

Ehkseliksis, Ink.

PYRROLE DERIVATIVES AS MEDICINAL SUBSTANCES Russian patent published in 2012 - IPC C07D207/325 C07D403/12 C07D405/10 C07D409/02 C07D417/02 A61K31/40

Abstract RU 2470916 C2

FIELD: chemistry.

SUBSTANCE: invention relates to pyrrole derivatives of formula I: , where values of R¹-R⁴, R⁷, R⁸ are given in claim 1. Compounds of formula I exhibit antagonistic activity on MR steroid receptors, which enables their use to produce a pharmaceutical composition and drugs with MR steroid receptor antagonist properties.

EFFECT: improved method.

95 cl, 26 dwg, 2 tbl, 32 ex

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RU 2 470 916 C2

Authors

Kanne Bannen Linn

Chen Dzheff

Dehlrimpl Liza Ehster

Flehtt Brenton T.

Forsajt Timoti Patrik

Gu Sjao-Khoj

Mehk Morrison B.

Mann Larri U.

Mann Grejs

Martin Richard

Mokhan Radzhu

Merfi Brehtt

Najman Majkl Charl'Z

Stivens Uill'Jam K. Ml.

Van Te-Lin'

Van Jun

Vu Dzhejson Kh.

Dates

2012-12-27—Published

2005-07-30—Filed