FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to a pressed tablet containing a pressed non-chewable base and a volatile active agent, preferentially menthol or eucalyptol included in a spray-dried granule additionally containing a starch carrier and a polyol granulating agent. The pressed tablet may be a two-layer tablet containing a sparkling layer and a non-sparkling layer with the spray-dried granule included in the sparkling layer. The tablets in the present application are effective to provide decongestant effects in a nasal cavity.
EFFECT: invention additionally refers to the use of starch for increasing release rate of the volatile active agent from the pressed tablet and improving its disintegration smoothness.
12 cl, 3 tbl, 2 ex
Authors
Dates
2013-01-20—Published
2009-03-10—Filed