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(19)

(11)

2 472 503

(13)

(51)

IPC

A61K31/415(2006-01-01)

A61K31/95(2006-01-01)

A61K33/30(2006-01-01)

A61P39/06(2006-01-01)

C09K15/32(2006-01-01)

(21) (22)

Application

2011148565/15, 2011-11-29

(24)

Start date

2011-11-29

(22)

Actual filing date

2011-11-29

(45)

Published

2013-01-20

(72)

Inventor

Sosin Denis VladimirovichParfenov Ehdgar AndreevichEvseev Andrej ViktorovichPravdivtsev Vitalij AndreevichEvseeva Marina Anatol'Evna

(73)

Holder

Gbou Vpo Gosudarstvennaja Meditsinskaja Akademija" Ministerstva Zdravookhranenija I Sotsial'Nogo Razvitija Rossijskoj Federatsii

ANTIHYPOXIC AGENT Russian patent published in 2013 - IPC A61K31/415 A61K31/95 A61K33/30 A61P39/06 C09K15/32

Abstract RU 2472503 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: what is presented is an antihypoxic agent differing by the fact that it represents a complex compound of divalent zinc substituted by 3-hydroxypyridine and diorganodichalcogenide - hexakis(3-hydroxy-2-ethyl-6-methylpyridinato)[tris(dibenzylselenido)dizinc(P)pentadeca-semihydrate of formula [Zn(II)]₂A₆B₃·15.5H₂O (the same πQ1983). [Zn(II)]₂A₆B₃·15.5H₂O wherein A: B:

EFFECT: efficacy of the reference antihypoxants (antisol, bemityl) is significatly second to πQ1983 by all resistance criteria to acutely developing hypoxia; unlike the reference antihypoxants, πQ1983 is still effective after the intake; reduces rectal temperature, slows down heart rate, reduces respiratory rate and depth, as well as body oxygen consumption; prolongs a period of cortex activity in acutely developing hypoxic condition.

4 dwg, 3 tbl

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RU 2 472 503 C1

Authors

Sosin Denis Vladimirovich

Parfenov Ehdgar Andreevich

Evseev Andrej Viktorovich

Pravdivtsev Vitalij Andreevich

Evseeva Marina Anatol'Evna

Dates

2013-01-20—Published

2011-11-29—Filed