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(19)

(11)

2 472 807

(13)

(51)

IPC

C07K16/24(2006-01-01)

C07K16/46(2006-01-01)

C12N15/13(2006-01-01)

C12P21/08(2006-01-01)

A61K39/395(2006-01-01)

A61P43/00(2006-01-01)

(21) (22)

Application

2009113026/10, 2007-09-07

(24)

Start date

2007-09-07

(22)

Actual filing date

2007-09-07

(45)

Published

2013-01-20

(72)

Inventor

Vu ChenbinDikson Richard V.Belk Dzhonatan P.In KhuaArdzhiriadi Marija A.Kaff Kehrolin A.Khinton Pol R.Kumar ShankarMelim Terri L.Chehn' Jan'

(73)

Holder

Ehbbott Lehboretriz

INTERLEUKIN-13 BINDING PROTEINS Russian patent published in 2013 - IPC C07K16/24 C07K16/46 C12N15/13 C12P21/08 A61K39/395 A61P43/00

Abstract RU 2472807 C2

FIELD: chemistry.

SUBSTANCE: disclosed is a binding protein which is specific to IL-13, having 6CDR sections (three light and three heavy chains). The invention discloses a structure of an antibody based on this protein and a conjugate based on the antibody. The invention describes versions of nucleic acid which codes the antibody or structure, and an expression vector, a replication vector and cells bearing such vectors. Described is a method of producing the protein by culturing cells and proteins obtained using said method. Described are compositions based on versions of the proteins.

EFFECT: invention can be used in medicine to treat and diagnose diseases associated with IL-13 activity which negatively affects health.

50 cl, 23 tbl, 2 ex

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RU 2 472 807 C2

Authors

Vu Chenbin

Dikson Richard V.

Belk Dzhonatan P.

In Khua

Ardzhiriadi Marija A.

Kaff Kehrolin A.

Khinton Pol R.

Kumar Shankar

Melim Terri L.

Chehn' Jan'

Dates

2013-01-20—Published

2007-09-07—Filed