FIELD: medicine.
SUBSTANCE: cell population is recovered from peripheral blood or umbilical blood by a method involving positive cell secretion from peripheral blood or umbilical blood able for immune reaction with an antibody specified in a group consisting of aHTH-CD44, anti-CD11b and their combination. The recovered myeloid-like cell population contains the cells expressing CD44 antigen, CD11b antigen and hypoxia-induced factor lα (HIF-lα). The prepared population is used for recovery and stabilisation of the functional vasculature, stimulation of microgliacyte formation, and for stimulation of physiologic intra-retinal vascularisation of hypoxic retinal tissue in simultaneous suppression of abnormal preretinal vessel formation.
EFFECT: invention enables preparing the cells with vasculotrophic and neurotrophic activity which possess a considerable therapeutic potential in the intraocular introduction into a mammal suffering a degenerative ocular disease.
7 cl, 63 dwg, 2 tbl, 21 ex
Authors
Dates
2013-01-27—Published
2007-11-16—Filed