DIAGNOSTIC TECHNIQUE FOR DEGREE OF HIP DISPLASIA IN CHILDREN Russian patent published in 2013 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: test samples are examined by ELISA technique. It is followed by evaluating the concentrations of type I collagen, aggrecan, hyaluronan, vasculoendothelial growth factor VEGF, fibroplastic growth factor FGF in a blood sample, and of type II collagen in an urine sample. The values, ng/ml: type I collagen within 2.71-3.03; type II collagen 3.60-3.82; aggrecan 79.17-84.35; hyaluronan 17.31-24.11; VEGF - 326.68-360.29; FGF - 9.21-11.31 enable diagnosing a mild degree; type I collagen within 3.04-3.83; type II collagen - 3.83-6.22; aggrecan - 84.36-105.62; hyaluronan - 24.12-32.36; VEGF - 360,30-482.14; FGF - 11.32-19.44 enable diagnosing a moderate degree, type I collagen within 3.84-5.85; type II collagen - 6.23-7.27; aggrecan - 105.63-134.45; hyaluronan - 32.37-87.68; VEGF - 482.15-839.30; FGF - 19.45-44.19 enable diagnosing a severe degree, type I collagen within 5.86-6.31; type II collagen - 7.28-7.82; aggrecan - 134.46-231.52; hyaluronan - 87.69-470.4; VEGF - 839.40-1047.19; FGF - 44.20-95.25 enable diagnosing an extreme degree.

EFFECT: invention enables providing higher objectivity of the diagnostic technique for a degree of hip dysplasia in children with improved result accuracy.

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