FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine, particularly a method of treating hyperglycemia and/or diabetes, reduction of glucose levels, as well as kits for treating. A method involves the meal-time rapid introduction of the GLP-1 dosage form into pulmonary circulation, e.g. by inhalation immediately into pulmonary alveolar capillaries with the use of a drug delivery system in the form of a dry powder wherein said therapeutically effective amount leads to the blood GLP-1 concentration which is 100 pmole/l or more.
EFFECT: method causes at least none side effects, such as excessive sweating, nausea and vomiting which are usually associated with the subcutaneous and intravenous introduction of glucagon-like peptide GLP-1.
25 cl, 8 ex, 6 tbl, 20 dwg
Title | Year | Author | Number |
---|---|---|---|
ACTIVE SUBSTANCE DELIVERY | 2008 |
|
RU2467741C2 |
PHARMACEUTICAL COMPOSITIONS, CONTAINING GLUCAGON-LIKE PEPTIDE (GLP-1) | 2007 |
|
RU2409349C2 |
PHARMACEUTICAL COMPOSITIONS, CONTAINING GLUCAGON-LIKE PEPTIDE 1 (GLP-1) | 2007 |
|
RU2542500C2 |
SYSTEMS AND METHODS FOR DRY POWDER DRUGS DELIVERY | 2011 |
|
RU2531455C2 |
SYSTEMS AND METHODS FOR DRY POWDER DRUG DELIVERY | 2011 |
|
RU2571331C1 |
DRY POWDER DRUG DELIVERY SYSTEMS AND METHODS | 2013 |
|
RU2650035C2 |
DIKETOPIPERAZIN MICROPARTICLES WITH PARTICULAR AMOUNT OF ISOMERS | 2010 |
|
RU2490026C1 |
APPLICATION OF SUPERFAST-ACTING INSULIN | 2009 |
|
RU2519706C2 |
USE OF SUPER-HIGH-SPEED INSULIN | 2014 |
|
RU2688663C2 |
METHOD OF IMPROVING PHARMACEUTICAL PROPERTIES OF PARTICLES, CONTAINING DIKETOPIPERAZINE AND ACTIVE AGENT | 2007 |
|
RU2403059C2 |
Authors
Dates
2013-02-10—Published
2008-10-24—Filed