METHOD FOR PREVENTING GLP-1 SIDE EFFECTS Russian patent published in 2013 - IPC A61K9/14 A61K38/26 A61P5/50 

Abstract RU 2474415 C2

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine, particularly a method of treating hyperglycemia and/or diabetes, reduction of glucose levels, as well as kits for treating. A method involves the meal-time rapid introduction of the GLP-1 dosage form into pulmonary circulation, e.g. by inhalation immediately into pulmonary alveolar capillaries with the use of a drug delivery system in the form of a dry powder wherein said therapeutically effective amount leads to the blood GLP-1 concentration which is 100 pmole/l or more.

EFFECT: method causes at least none side effects, such as excessive sweating, nausea and vomiting which are usually associated with the subcutaneous and intravenous introduction of glucagon-like peptide GLP-1.

25 cl, 8 ex, 6 tbl, 20 dwg

Similar patents RU2474415C2

Title Year Author Number
ACTIVE SUBSTANCE DELIVERY 2008
  • Boumen Robert A.
  • Richardson Piter
  • Kostello Donal'D
  • Leone-Behj Andrea
RU2467741C2
PHARMACEUTICAL COMPOSITIONS, CONTAINING GLUCAGON-LIKE PEPTIDE (GLP-1) 2007
  • Grin Stefani
  • Brandt Dehvid
  • Gel'Ber Kokhava
  • King Mark
  • Chizam Vehjman Vehndell
  • Oberg Kit
  • Leone-Behj Andrea
  • Khoukenson Mark Dzh.
  • Fejris Mehri
RU2409349C2
PHARMACEUTICAL COMPOSITIONS, CONTAINING GLUCAGON-LIKE PEPTIDE 1 (GLP-1) 2007
  • Grin Stefani
  • Brandt Dehvid
  • Gel'Ber Kokhava
  • King Mark
  • Chizam Vehjman Vehndell
  • Oberg Kit
  • Leone-Behj Andrea
  • Khoukenson Mark Dzh.
  • Fejris Mehri
RU2542500C2
SYSTEMS AND METHODS FOR DRY POWDER DRUGS DELIVERY 2011
  • Smatni Chad S.
  • Adamo Benua
  • Polidoro Dzhon M.
  • Kinsi P. Spenser
  • Overfild Dennis
  • Sakhi Karl
  • Billings Kristin
  • Marino Mark T.
RU2531455C2
SYSTEMS AND METHODS FOR DRY POWDER DRUG DELIVERY 2011
  • Smatni Chad S.
  • Adamo Benua
  • Polidoro Dzhon M.
  • Kinsi P. Spenser
  • Overfild Dennis
  • Sakhi Karl
  • Billings Kristin
  • Marino Mark T.
RU2571331C1
DRY POWDER DRUG DELIVERY SYSTEMS AND METHODS 2013
  • Smatni Chad S.
  • Adamo Benua
  • Laurentsi Brendan F.
  • Kinsi P. Spenser
RU2650035C2
DIKETOPIPERAZIN MICROPARTICLES WITH PARTICULAR AMOUNT OF ISOMERS 2010
  • Kraft Kelli S.
  • Somervill Karla
RU2490026C1
APPLICATION OF SUPERFAST-ACTING INSULIN 2009
  • Richardson Piter
  • Boumen Robert A.
  • Potoka Ehlizabet
  • Boss Anders Khasager
  • Petruchchi Richard
  • Govard Kehmpbell
  • Mann Al'Fred
RU2519706C2
USE OF SUPER-HIGH-SPEED INSULIN 2014
  • Richardson Piter
  • Boumen Robert A.
  • Potoka Elizabet
  • Boss Anders Khasager
  • Petruchchi Richard
  • Govard Kempbell
  • Mann Alfred
RU2688663C2
METHOD OF IMPROVING PHARMACEUTICAL PROPERTIES OF PARTICLES, CONTAINING DIKETOPIPERAZINE AND ACTIVE AGENT 2007
  • Uilson Brajan R.
  • Grant Marshall
RU2403059C2

RU 2 474 415 C2

Authors

Richardson Piter

Boumen Robert A.

Kostello Donal'D

Dates

2013-02-10Published

2008-10-24Filed