FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to field of medicine, namely to pharmaceutical industry and deals with disulfiram-based medication, which additionally contains corticosteroid. Medicine contains 59.5-97.0 wt % of disulfiram base, 0.5-3.0 wt % of corticosteroid, 2.0-37.0 wt % of nitrogen-containing polymer composition and 0.2-0.5 wt % of stearic acid or magnesium stearate. Composition of nitrogen-containing polymers includes copolymer of N-vinylpyrrolidone and 2-methyl-5-vinylpyridine or salts of dissolved oligomers of hexamethylenediamine and guanidine and polyvinylpyrrolidone.
EFFECT: medication can be applied in addictology for treatment of alcohol or opiate-dependent patient.
2 cl, 4 ex, 2 tbl
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Authors
Dates
2013-02-20—Published
2012-02-29—Filed