FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine and describes a disulphiram implant for treating the alcohol or opiate addictive patients. The implant contains disulphiram 95.0-59.0 wt %, nitrogen polymer composition 4.8-40.5 wt % and stearic acid or magnesium stearate 0.2-0.5 wt %. The nitrogen polymer composition contains N-vinylpyrrolidone and 2-methyl-5-vinylpyridine copolymer or salts of branched oligomers hexamethylene diamine and guanidine, and polyvinylpyrrolidone.
EFFECT: implant may be used in addictology and provides a prolonged and uniform release of disulphiram with improving incisional wound healing.
5 ex, 2 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| IMPLANTABLE MEDICATION DISULFIRAM-BASED FOR TREATMENT OF ALCOHOL OR OPIATE-DEPENDENT PATIENT | 2012 |
|
RU2475272C1 |
| IMPLANTED DRUG PREPARATION OF NALTREXONE FOR TREATING ALCOHOL- OR OPIOID-DEPENDENT PATIENTS | 2012 |
|
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| OPHTHALMIC PREPARATION PRESENTED IN FORM OF EYE DROPS AND CONTAINING BRANCHED POLYHEXAMETHYLENE GUANIDINES AND POLY(N-VINYLPYRROLIDONE) | 2012 |
|
RU2509562C1 |
| PHARMACEUTICAL COMPOSITION FOR TREATING ALCOHOLISM, DRUG ADDICTION AND CHEMICAL ABUSE WITH IMPROVED NALTREXONE RELEASE PROFILE | 2011 |
|
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| COPOLYMERS OF 4-VINYLPYRIDINE OR 2-METHYL-5-VINYLPYRIDINE AND N-VINYLPYRROLIDONE WITH TERMINAL CYANOVALERIC ACID RESIDUE AND USE THEREOF TO TREAT PNEUMOCONIOSIS | 2014 |
|
RU2550820C1 |
| DISULFIRAM AND TAURINE-CONTAINING OPHTHALMOLOGICAL MEDICATION IN FORM OF EYE DROPS | 2012 |
|
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| OPHTHALMIC PREPARATION PRESENTED IN FORM OF EYE DROPS AND CONTAINING BRANCHED POLYHEXAMETHYLENE GUANIDINES | 2012 |
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| SOLID DOSAGE FORM OF TAURINE WITH IMPROVED PHARMACOLOGICAL PROPERTIES | 2012 |
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|
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| N-VINYLPYRROLIDONE-BASED COPOLYMERS IN FORM OF PHARMACEUTICALLY ACCEPTABLE SALTS OF ACIDS | 2013 |
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RU2533113C1 |
