FIELD: chemistry.
SUBSTANCE: present invention relates to compounds of formula I
,
wherein radicals and symbols assume values given in the claim, or pharmaceutically acceptable salts thereof. The disclosed compounds inhibit serine protease activity, especially activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, compounds of the present invention inhibit the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to a pharmaceutical composition containing said compounds for administering to a patient suffering from HCV infection.
EFFECT: invention also relates to a method of treating HCV infection in a patient and a method of inhibiting replication of hepatitis C virus by administering a pharmaceutical composition containing compounds of the present invention.
7 cl, 7 tbl, 158 ex
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