FIELD: biotechnologies.
SUBSTANCE: immortalised embryonal cell of birds or cells that originate from it, contains a nucleic-acid sequence E1A, for replication of a virus or for production of a target substance or virus. The immortalised embryonal cell is produced by the method including the stage of transfection of this cell with a non-virus vector, containing the specified nucleic-acid sequence E1A and the nucleic-acid sequence, which codes the recombinant reverse transcriptase of telomerase. Besides, cells that originate from the specified cell represent cells that develop or differentiate from it or have it as an ancestor.
EFFECT: cells according to the invention, in particular, are useful for production of recombinant virus vectors.
37 cl, 10 dwg, 4 ex
| Title |
Year |
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Number |
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|
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|
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|
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