METHOD OF PRODUCING TARGET VIRUS OR TARGET PROTEINS DIFFERENT FROM ADENOVIRUS, EXPRESSION CELL AND HOST CELL AND PRODUCTION METHODS THEREOF, USE OF EXPRESSION CELL Russian patent published in 2012 - IPC C12N7/01 C12N5/10 C07K14/01 

FIELD: chemistry.

SUBSTANCE: present invention relates to biotechnology and genetic engineering. The method of producing a target virus or one or more target proteins different from adenovirus involves culturing an expression spinal cell and extracting the end product. The cell is a spinal cell containing a gene which is stably integrated into its genome, where said gene codes PIX adenovirus or its functional version, as heterologous regulatory protein. The cell stably expresses said regulatory protein or its functional version via a target virus which is not adenovirus or via a vector carrying nucleic acid sequences which code said virus or via a vector carrying nucleic acid sequences which code said one or more target proteins.

EFFECT: disclosed method enables to increase output of the end product.

24 cl, 18 dwg, 15 ex