CHITOSAN CARBOXYALKYLAMIDE HYDROGEL, PREPARING IT AND USING IN COSMETOLOGY AND DERMATOLOGY Russian patent published in 2013 - IPC A61K8/02 C08L5/08 C08J3/02 A61K31/722 A61K36/28 A61P17/02 A61K8/73 A61K9/06 A61K9/19 A61Q19/00 

Abstract RU 2476201 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to chitosan carboxyalkylamide hydrogel and may be used for cosmetic and dermatological treatment of skin burns. Chitosan carboxyalkylamide hydrogel of pH close to that of skin and making 6.5 to 7.2 contains 40 to 90 mole % of the groups of N-carboxyalkylaminde D-glucosamine of formula (I) wherein n represents an integer 1 to 8, 60 to 10 mole % of the protic groups of D-glucosamine, and 5 to 15 mole % of the groups of N-acetyl-D-glucosamine. A method for preparing said hydrogel involves preparing an acid solution of chitosan of a degree of acetylation of 85 to 95%, providing a reaction of produced additive chitosan salt in an aqueous solution of diorganic acid and correcting pH of the prepared solution.

EFFECT: preparing the anhydrous product of chitosan carboxyalkylamide prepared by hydrogel dehydration.

12 cl, 1 dwg

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RU 2 476 201 C2

Authors

Lozh'E Ehlizabet

Gushe Frank

Perro Zhan-P'Er

Dates

2013-02-27Published

2008-07-01Filed