FIELD: medicine.
SUBSTANCE: invention refers to medicine. What is described is a solution for preparing a chitosan material, methods for preparing the haemostatic material of the solution and a medical device with using chitosan fibres. The solution consists of the following ingredients in ratio of total amount of the solution, wt %: dry chitosan with a degree of deacetylation - not less than 80%: 4-8 at dry basis, an aqueous solution of a polymer or a mixture of polymers: 1-10 at dry basis, an aqueous solution of an organic acid or a mixture of organic acids in the concentration of 50 - 80% - the rest. The method for preparing the haemostatic material of the aqueous-acidic solution containing a polyelectrolyte complex of chitosan and a water-soluble polymer comprising the electrochemical treatment of the chitosan solution in an electric field with a conductive substrate. The electrospun fibres have the following characteristics: viscosity - 1.4-2.5 Pa·s, surface tension - 31-35 mN/m and electrical conductivity no more than 2.3 mSm/cm due to the use of a viscoelastic solution.
EFFECT: method enables the chitosan fibre of a thinner diameter.
45 cl, 20 dwg, 6 tbl, 16 ex
Title | Year | Author | Number |
---|---|---|---|
MULTILAYER MATERIAL WITH CHITOSAN LAYER OF NANOFIBRES AND SUPERFINE FIBRES | 2013 |
|
RU2522216C1 |
HEMOSTATIC AGENT BASED ON CHITOSAN AEROGEL | 2020 |
|
RU2743425C1 |
HEMOSTATIC AGENT BASED ON CHITOSAN | 2023 |
|
RU2807862C1 |
BIOPOLYMERIC FIBRE, COMPOSITION OF FORMING SOLUTION FOR ITS OBTAINING, METHOD OF FORMING SOLUTION PREPARATION, LINEN OF BIOMEDICAL PURPOSE, BIOLOGICAL BANDAGE AND METHOD OF WOUND TREATMENT | 2010 |
|
RU2468129C2 |
METHOD OF OBTAINING HEMOSTATIC AGENT BASED ON CHITOSAN | 2023 |
|
RU2806364C1 |
METHOD OF OBTAINING CHITOSAN MICROTUBES (VERSIONS) | 2014 |
|
RU2564921C1 |
NANOFIBRE-BASED COMPOSITE POLYMERIC WOUND COATING | 2017 |
|
RU2647609C1 |
WOUND HEALING AND HAEMOSTATIC AGENT BASED ON CHITOSAN AND A METHOD FOR PRODUCTION THEREOF | 2019 |
|
RU2709462C1 |
FOOD MATERIAL FILM MATERIAL BASED ON CHITOSAN AND METHOD FOR PRODUCTION THEREOF | 2017 |
|
RU2682598C2 |
METHOD FOR FORMING CHITOSAN FILM COATING AND CHITOSAN FILM COATING | 2010 |
|
RU2461575C2 |
Authors
Dates
2013-07-20—Published
2011-07-26—Filed