SOLUTION FOR PREPARING CHITOSAN MATERIAL, METHOD FOR PREPARING HAEMOSTATIC MATERIAL OF THIS SOLUTION (VERSIONS) AND MEDICAL DEVICE WITH USING CHITOSAN FIBRES Russian patent published in 2013 - IPC A61K9/08 A61K31/722 A61L15/28 A61P7/04 B28B1/00 

Abstract RU 2487701 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine. What is described is a solution for preparing a chitosan material, methods for preparing the haemostatic material of the solution and a medical device with using chitosan fibres. The solution consists of the following ingredients in ratio of total amount of the solution, wt %: dry chitosan with a degree of deacetylation - not less than 80%: 4-8 at dry basis, an aqueous solution of a polymer or a mixture of polymers: 1-10 at dry basis, an aqueous solution of an organic acid or a mixture of organic acids in the concentration of 50 - 80% - the rest. The method for preparing the haemostatic material of the aqueous-acidic solution containing a polyelectrolyte complex of chitosan and a water-soluble polymer comprising the electrochemical treatment of the chitosan solution in an electric field with a conductive substrate. The electrospun fibres have the following characteristics: viscosity - 1.4-2.5 Pa·s, surface tension - 31-35 mN/m and electrical conductivity no more than 2.3 mSm/cm due to the use of a viscoelastic solution.

EFFECT: method enables the chitosan fibre of a thinner diameter.

45 cl, 20 dwg, 6 tbl, 16 ex

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Authors

Vnuchkin Aleksandr Vasil'Evich

Nasibulina Evgenija Rushanovna

Zabivalova Natal'Ja Mikhajlovna

Dates

2013-07-20Published

2011-07-26Filed