ORDERED MESOPOROUS SILICON OXIDE MATERIAL Russian patent published in 2013 - IPC C01B37/02 A61K9/16 

Abstract RU 2476377 C2

FIELD: chemistry.

SUBSTANCE: invention relates to materials based on silicon oxides. Ordered mesoporous silicon oxide material with uniform in size pores in range from 4 to 30 nm is characterised by ratio Q3 to Q4 for silicon atoms smaller than 0.65. Material is synthesised in weakly acidic or neutral conditions with application of alkali metal silicate, amphiphilic blockcopolymer, buffer with pH within the interval from 5 to 7 and, possibly, compound ammonium tetraalkyl. Material has two-dimensional hexagonal structure of ordered mesoporous silicon oxide materials, designated SOK-12. Size of mezopores is preferably in the range from 4 to 12 nm. Size of pores can be precisely regulated by varying synthesis conditions.

EFFECT: obtained ordered mesoporous silicon oxide materials are efficient in their application as materials-carriers for molecules of poorly soluble drugs and for peroral drug forms with immediate release.

13 cl, 48 dwg, 2 tbl, 24 ex

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RU 2 476 377 C2

Authors

Jammar Jasper

Arts Aleksander

Van Den Moter Gi

Martens Jokhan

Dates

2013-02-27Published

2009-04-28Filed