FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to a method for preparing a hydrophilic mesh polymer sorbent for selective sorption of erythromycin from a culture medium, involving radical copolymerisation of a non-ionic monomer, a template monomer, a cross-linking agent in the presence of a oxidation-reduction system (ammonium sulphate - ascorbic acid - 1 wt % to monomer weight) differing by the fact that the non-ionic monomer is 2-hydroxy ethylmethacrylate; the template monomer is erythromycin methacrylate; the cross-linking agent is ethylene glycol dimethacrylate, and the copolymerisation process is conducted at room temperature in an inert atmosphere in 50% aqueous isopropanol in the concentration of comonomers in the solution of 20 wt % solution containing the cross-linking agent 25 mole % and the relation of the non-ionic monomer: template monomer 72-3:60-15 mole %.
EFFECT: preparing the sorbent possessing high erythromycin sorption capacity.
1 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PRODUCING CELLULAR POLYMER SORBENT FOR SELECTIVE SORPTION OF ENDOTOXIN FROM BLOOD PLASMA | 2010 |
|
RU2439089C1 |
| METHOD FOR SYNTHESIS OF CROSS-LINKED POLYMERIC PLASMA SORBENT, MOLERCULARLY IMPRINTED WITH URIC ACID | 2010 |
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| METHOD FOR PRODUCING SELECTIVE SORBENT FOR SOLID-PHASE EXTRACTION OF PYRROLIDONE DERIVATIVES FROM BIOLOGICAL FLUIDS | 2020 |
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| CROSS-LINKED COPOLYMERS OF 1-VINYL-1,2,4-TRIAZOLE WITH DIVINYL SULFIDE AS SORBENTS OF PRECIOUS METALS AND METHOD FOR THEIR PREPARING | 2006 |
|
RU2321600C2 |
| 1-VINYL-1,2,4-TRIAZOLE NETWORK COPOLYMERS WITH DIVINYL ESTER OF DIETHYLENE GLYCOL AS SORBENTS OF NOBLE METALS FROM ACIDIC MEDIA AND METHOD OF OBTAINING THEM | 2006 |
|
RU2326131C2 |
| UNSATURATED DERIVATIVES OF CARBONYLPYRIDINIUM BROMIDEOXIMES AS MONOMERS FOR SYNTHESIS OF POLYMERIC HYDROGELS | 0 |
|
SU1705277A1 |
| METHOD OF PRODUCING POLYMER HYDROGELS WITH COVALENT-BONDED OXIME GROUPS | 0 |
|
SU1713905A1 |
| METHOD OF OBTAINING FORMED ION-EXCHANGE MATERIAL | 0 |
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SU951852A1 |
| METHOD OF OBTAINING CARBOXYL CATIONITE | 0 |
|
SU562093A1 |
| METHOD FOR PREPARING MACROCROSS-LINKED ANIONOTE | 2003 |
|
RU2243242C1 |
