METHOD FOR SPERMATOGENESIS CORRECTION IN ANIMALS IN CHRONIC NATURAL GAS POISONING Russian patent published in 2013 - IPC A61K33/04 A61K31/375 A61P15/08 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to molecular physiology and biochemistry, and may be used for normalizing spermatogenesis in animals in chronic natural gas poisoning. The method for spermatogenesis correction in animals suffered chronic natural gas poisoning, consisting in the use of selenium-containing preparations, and a correcting preparation is Selexen used in a combination with ascorbic acid administered orally to male albino rats in doses of 1.5 mg/kg and 500 mg/kg of animal's body weight, respectively once a day for 50 days, and at the same time from the third week of the administration of Selexen and ascorbic acid, the animals are exposed to sulphurous natural gas in the concentrations of 10 mg/m³ for 30 days, 240 minutes a day, and upon the completion of the experimental exposure, the morphological and kinetic parameters of spermatogenesis are to be examined.

EFFECT: implemented reduction of the toxic effects of natural gas on the reproductive function of male gonads.

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