METHOD FOR ASSESSING SPERMATOGENESIS CORRECTION EFFICACY IN ANIMALS EXPOSED FOR MICROWAVE RADIATION Russian patent published in 2015 - IPC G01N33/483 

Abstract RU 2552924 C1

FIELD: medicine.

SUBSTANCE: testicular germ cells are measured quantitatively. That is ensured by 50-day oral administration of selexen and ascorbic acid into male white rats in doses 1.5 and 500 mg/kg of animal's body weight respectively once a day. 14 days later, administering the selenium-containing biocomplex is accompanied by the 30-minute daily exposure to microwave radiation at 42 GHz (λ=7.1 mm) for 30 days. Once the experimental exposures are completed, the corrective properties of the biocomplex as having an effect on the morphofunctional state of epididymal sperm cells are assessing by formula: MFSI=A+B, wherein MFSI is a morphofunctional state index, A is a portion of normal sperm cells in relation to the reference, and B is a portion of moving sperm cells in relation to the reference. If the MFSI value is 1.3 or more, the spermatogenesis correction is considered to be ineffective, while the MFSI value being more than 1.3 shows the effective spermatogenesis correction if exposed to microwave radiation.

EFFECT: invention enables assessing the spermatogenesis correction efficacy with underlying administration of the biocorrector.

2 tbl, 3 dwg, 3 ex

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RU 2 552 924 C1

Authors

Loginov Pavel Vadimovich

Nikolaev Aleksandr Arkad'Evich

Dates

2015-06-10Published

2014-05-13Filed