MULTIPOTENT MESENCHYMAL STEM CELL CULTURE RECOVERED FROM BOVINE BONE MARROW (Medulla ossium Bos taurus) FOR PURPOSES OF VETERINARY SCIENCE, CELL AND TISSUE ENGINEERING Russian patent published in 2013 - IPC C12N5/775 

FIELD: medicine.

SUBSTANCE: invention refers to veterinary medicine and biotechnology, and concerns a bovine multipotent mesenchymal stem cell (MMSC) culture. The presented culture is recovered from the bovine bone marrow, capable to form the cells of other tissues in induction in vitro: bone, muscle and fat, has no admixture of hematopoietic and endothelial cells, has an immune phenotype characteristic for mammalian MMSCs and endothelial cells, able to be preserved in the culture for a long time. The described cell culture is deposited in the Special Collection of passaged somatic cell cultures of agricultural and food animals of Kovalenko All-Russian Research Institute of Experimental Veterinary Science (SHZh RASHN), No. 79.

EFFECT: culture may be used in regeneration and repair of tissues and organs of agricultural animals, in studying of the infectious mechanisms at the cellular and tissue levels in vitro; furthermore, the presented cell culture may be used to create a cell-based systems for pathogen growth in vitro.

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