THERAPEUTIC ANALGESIC Russian patent published in 2013 - IPC A61K31/551 A61K45/00 A61P29/00 A61P35/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: what is presented is a therapeutic and/or preventive agent for cancer pain which may be administered to the patient for a long time from the earliest to the last stage instead of conventional non-opioid or opioid analgesics in a daily dose for adults from 50 to 600 mg. As an active ingredient, the agent comprises a compound of formula (I) or its acceptable salt thereof (particularly, (R)-(-)-3-[3-(1-tert-butylcarbonylmethyl-2-oxo-5-cyclohexyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-3-yl)ureido]benzoic acid or (version) a combination with an opioid analgesic. What is presented is the use of the compound of formula (I) or a salt thereof to prepare the above agent in a daily dose of 50 to 600 mg (version - a combination with the opioid analgesic) and a related method of treating (versions). What is shown is relieving pain under action of the compound of formula (I) not related with the effect of tumour regression.

EFFECT: compound causes no serious side effects normally caused by the non-opioid and opioid analgesics.

18 cl, 3 dwg