FIELD: medicine; pharmaceutics.
SUBSTANCE: invention relates to medicine and pharmaceutics and relates to a combination of a compound of general formula (I) or a pharmacologically acceptable acid addition salt thereof and a ghrelin receptor agonist, which is anamorelin or a pharmaceutically acceptable salt thereof, as well as use of such a combination for preparing a drug for treating or preventing cachexia. In general formula (I), the double line consisting of the dotted line and the solid line is a double bond or a single bond, R1 is cyclopropylmethyl, R2 is methyl, and B is a trans-form -CH = CH-.
EFFECT: using the invention enables treating or preventing cachexia effectively.
4 cl, 6 dwg, 3 ex
