PHARMACEUTICAL COMPOSITION OF VALSARTAN Russian patent published in 2013 - IPC A61K31/41 A61K31/549 A61K47/00 A61K9/10 A61P9/04 A61P9/10 A61P9/12 A61P13/12 A61P25/00 

Abstract RU 2487710 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to a pharmaceutical composition the form of an oral suspension consisting of valsartan or a pharmaceutically acceptable salt thereof and at least one or two or more ingredients specified in glycerol or a syrup or a mixture thereof, a preserving agent, a buffer system, a suspending/stabilising agent and anti-foaming agent. The buffer system is specified in sodium citrate, potassium citrate, sodium bicarbonate, sodium dihydrophosphate and potassium dihydrophosphate, and maintains pH of the composition within the range of 3.0 to 5.0. Further, the present invention refers to using the pharmaceutical composition for preparing a drug.

EFFECT: orally administered valsartan suspension provides high bioavailability and reduced variability of response to the administered dose when administered to different subjects or one subject.

10 cl, 4 tbl, 2 ex

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RU 2 487 710 C2

Authors

Talamonti Uehjn

Uogner Robert Frank

Vehn' Khon

Dates

2013-07-20Published

2008-10-07Filed