FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to pharmacy and medicine, and concerns using the pyridopyrazine derivatives for preparing a drug for treating or preventing the physiological and/or pathophysiological conditions associated withPI3K kinase inhibition in mammals.
EFFECT: invention provides high clinical effectiveness.
7 cl, 4 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PYRIDO[2,3-b]PYRAZINE DERIVATIVES, MEDICINE FOR TREATMENT OF DISEASES OR ABNORMALITIES CAUSED BY MISDIRECTED CELLULAR SIGNAL TRANSDUCTION PROCESSES, METHOD OF MEDICINE OBTAINING | 2004 |
|
RU2330851C9 |
| PYRIDOPYRAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATING OR PREVENTING PHYSIOLOGICAL AND/OR PATHOPHYSIOLOGICAL CONDITIONS BY INHIBITION OF ENZYMES ERK, ERK1, ERK2, PI3K, PI3Kalpha, PI3Kbeta, PI3Kgamma, PI3Kdelta, PI3K-C2alpha, PI3K-C2beta, PI3K-Vps34p (VERSIONS) | 2006 |
|
RU2515944C9 |
| QUINOXALINE DERIVATIVES AND USING THEM FOR TREATING BENIGN AND MALIGNANT TUMOUR DISEASES | 2010 |
|
RU2532914C2 |
| PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | 2009 |
|
RU2473549C2 |
| NOVEL NAPHTHYRIDINE DERIVATIVES AND THEREOF APPLICATION AS KINASE INHIBITORS | 2010 |
|
RU2573390C2 |
| DERIVATIVES OF 6-ARYLPYRIDO[2,3-D]PYRIMIDINES AND -NAPHTHYRIDINES, PHARMACEUTICAL COMPOSITION SHOWING INHIBITORY EFFECT ON CELLULAR PROLIFERATION INDUCED BY PROTEIN TYROSINE KINASE AND METHOD OF INHIBITION OF CELLULAR PROLIFERATION | 1995 |
|
RU2191188C2 |
| CONDENSED TRIAZOLAMINES AS P2X7 MODULATORS | 2010 |
|
RU2533122C2 |
| CYCLIC INHIBITORS OF PROTEIN-TYROSINE KINASE | 2000 |
|
RU2312860C2 |
| BICYCLIC DERIVATIVES OF IMIDAZO-3-YLAMINE, METHOD FOR THEIR PREPARING AND MEDICINAL AGENT BASED ON THEREOF | 2000 |
|
RU2264402C2 |
| COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEREOF AND METHOD FOR TREATMENT OF CYTOKINE-MEDIATED DISEASE | 2000 |
|
RU2298008C2 |
