METHOD FOR DIFFERENTIATED STIMULATION OF TISSUE REPAIR AND REGENERATION ACCOMPANYING INTRA-ARTICULAR FRACTURES OF COTYLOID CAVITY Russian patent published in 2013 - IPC A61M25/00 A61K31/375 A61K31/7004 A61K33/14 A61K35/16 A61P19/02 A61B17/56 G09B23/28 

FIELD: medicine.

SUBSTANCE: invention refers to experimental medicine and may be used to study the stimulation of the reparative processes in tissues of an involved joint. That is ensured by simulating the intra-articular fracture of the cotyloid cavity. The stimulation involves the restoration of anatomic relationships in the joint, the stabilisation thereof with an external fixation apparatus. Later, starting from the second postoperative day, a solution or a mixture of solutions is introduced drop-by-drop into the joint cavity for 3-5 days. Differentiating in the osteoblastic direction and forming a preferential bone fusion requires a mixture of officinal solutions of 40% glucose, 5% ascorbic acid, autologous blood plasma, taken in a volume ratio of 1:2:7 to be introduced. For the purpose of the fibroblast differentiation and formation of a preferential connective tissue fusion, a mixture of officinal solutions of 5% glucose and 5% ascorbic acid in the volume ratio 1:1 is introduced. Differentiating in the chondroblastic direction and forming a preferential cartilage fusion are ensured by introducing officinal 0.9% sodium chloride solution.

EFFECT: method provides the targeted regulation of the reparative processes in tissues of the involved joint.

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