METHOD OF ASSESSING INFLUENCE OF HERPES VIRUS INFECTION ON ERYTHROCYTE MEMBRANE STABILITY IN NEWBORNS OF MOTHERS SUFFERED AGGRAVATED HERPES VIRUS INFECTION IN THIRD TRIMESTER OF PREGNANCY Russian patent published in 2013 - IPC G01N33/48 

Abstract RU 2488112 C1

FIELD: medicine.

SUBSTANCE: newborn's peripheral blood is examined for malondialdehyde (MDA), and newborn's erythrocyte membrane α-spectrin is determined by disk electrophoresis in polyacrylamide gel (10%) with sodium dodecyl sulphate; a discriminant function is calculated by formula as follows: Df=(-4.131×α-spectrin)+(+14.334×MDA); wherein Df is a discriminant function; α-spectrin is erythrocyte stromal protein as a part of the erythrocyte membranes; MDA is a fatty acid peroxidation product in newborn's peripheral blood. If Df is more than (-0.235), a threatening instability of newborn's erythrocyte membranes is predicted that can lead to developing prenatal anaemia.

EFFECT: higher accuracy of the prediction procedure.

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RU 2 488 112 C1

Authors

Lutsenko Mikhail Timofeevich

Andrievskaja Irina Anatol'Evna

Dates

2013-07-20Published

2012-02-03Filed