DIAGNOSTIC TECHNIQUE FOR RED-CELL MEMBRANE COMPETENCE IN PERIPHERAL BLOOD OF PREGNANT WOMEN SUFFERING FROM HERPES VIRAL INFECTION Russian patent published in 2009 - IPC G01N33/49 G01N33/92 G01N33/68 

Abstract RU 2367953 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine and can be used to monitor the damaging action of herpes viral infection on red-cell membrane competence. There is offered diagnostic technique for red-cell membrane competence in peripheral blood of pregnant women suffering from exacerbated herpes viral infection. The technique is characterised that by disk step gradient polyacrylamide 10% gel electrophoresis with sodium dodecyl sulphate, healthy pregnant women and pregnant women suffering from exacerbated herpes viral infection are examined for the content of α-spectrin, β-spectrin and protein band 4.1in red-cell membranes. If α-spectrin is decreased to 6.8±0.02 standard units, β-spectrin - to 7.1±0.08 standard units, while protein band 4.1 is decreased to 3.2±0.05 standard units, red-cell membrane incompetence is diagnosed that causes gain in degenerate red-cell forms count.

EFFECT: traceability of damaging action of herpes viral toxins in exacerbated infection on red-cell cytoskeleton of peripheral blood.

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RU 2 367 953 C1

Authors

Lutsenko Mikhail Timofeevich

Andrievskaja Irina Anatol'Evna

Dates

2009-09-20Published

2008-04-21Filed