USING MATRIC METALLOPROTEINASE-10 (MMP-10) FOR THROMBOLYTIC THERAPY Russian patent published in 2013 - IPC A61K38/48 

Abstract RU 2489163 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to using matrix metalloproteinase-10 for preparing pharmaceutical combinations applicable for thrombolytic therapy, as well as to pharmaceutical combinations for treating thrombolytic disorders and to a method of thrombolytic therapy. The present combination may also contain a plasminogen activator.

EFFECT: group of inventions provides the alternative therapeutic combinations for thrombolytic therapy which contribute to fibrinolysis by selective degradation of fibrin and help to minimise the adverse effects related to the thrombolytic therapy.

26 cl, 6 dwg, 1 tbl, 4 ex

Similar patents RU2489163C2

Title Year Author Number
COMPOSITIONS FOR ANTIFIBRINOLYTIC TREATMENT 2008
  • Orbe-Lopategi Khosune
  • Paramo-Fernandes Khose-Antonio
  • Rodriges-Garsija Khose-Antonio
  • Serrano-Vargas Rosario
RU2453337C2
PHARMACEUTICAL COMPOSITION COMPRISING FACTOR VIIA AND FACTOR XIII 2001
  • Petersen Lars Kristian
  • Khedner Ulla
  • Rejk'Er Rasmus
RU2272648C2
METHOD OF PRODUCTION OF PLASMINOGEN ACTIVATOR 2007
  • Isaev Vjacheslav Artashesovich
  • Semenova Svetlana Aleksandrovna
  • Ljutova Ljudmila Vasil'Evna
  • Rudenskaja Galina Nikolaevna
  • Medvedeva Elena Aleksandrovna
RU2346983C1
PLASMINOGEN AND PLASMIN VARIANTS 2012
  • Zwaal Richard Reinier
RU2604807C2
RECOMBINANT POLYPEPTIDE WITH HUMAN PLASMINOGEN PROPERTIES TO CONVERT INTO PLASMIN IF ACTIVATED WHICH CATALYSES FIBRIN SPLITTING, DNA FRAGMENT CODING POLYPEPTIDE, RECOMBINANT PLASMID DNA FOR POLYPEPTIDE EXPRESSION AND TRANSFORMED Escherichia coli CELL - POLYPEPTIDE PRODUCER 2009
  • Bibilashvili Robert Shalvovich
  • Belogurov Anatolij Aleksandrovich
  • Gurskij Jaroslav Georgievich
  • Minashkin Mikhail Mikhajlovich
  • Skamrov Andrej Viktorovich
  • Skrypina Natalija Alekseevna
  • Feoktistova Evgenija Sergeevna
RU2432396C2
PHARMACEUTICAL COMPOSITION ELICITING THROMBOLYTIC AND FIBRINOLYTIC EFFECT 2002
  • Belogurov A.A.
  • Bibilashvili R.Sh.
  • Gurskij Ja.G.
  • Del'Ver E.P.
  • Tovarova I.I.
RU2216348C1
PLASMINOGEN AND PLASMIN VARIANTS 2012
  • Zwaal Richard Reinier
RU2604810C2
THROMBOLYTICS FOR INTRAVASCULAR THROMBI 2020
  • Hong, Seong Tshool
  • Kim, Hyeon Jin
  • Hassan, Mdmehedi
RU2822136C1
RECOMBINANT PLASMID DNA pBK415 CODING POLYPEPTIDE OF RECOMBINANT TISSULAR ACTIVATOR OF PLASMINOGEN OF HUMAN BEING, CELL LINE Cricetulus griseus CHO 1F8-PRODUCER OF RECOMBINANT TISSULAR ACTIVATOR OF PLASMINOGEN OF HUMAN BEING, AND METHOD FOR OBTAINING AND SEPARATION OF POLYPEPTIDE HAVING ACTIVITY OF TISSULAR ACTIVATOR OF PLASMINOGEN 2012
  • Grigor'Eva Ol'Ga Vasil'Evna
  • Zaval'Nyj Mikhail Aleksandrovich
  • Karpov Andrej Pavlovich
  • Petrov Andrej Vladimirovich
  • Fabrichnyj Igor' Pavlovich
  • Shuster Aleksandr Mikhajlovich
RU2500817C1
COMBINATION OF THROMBOLYTICALLY ACTIVE PROTEINS AND ANTICOAGULANTS 1995
  • Ul'Rikh Martin
  • Shtefan Fisher
RU2166326C2

RU 2 489 163 C2

Authors

Orbe-Lopategi Khosune

Rodriges-Garsija Khose-Antonio

Paramo-Fernandes Khose-Antonio

Serrano-Vargas Rosario

Dates

2013-08-10Published

2008-02-11Filed