COMPOSITIONS OF STABLE ELSAMITRUCIN SALTS Russian patent published in 2013 - IPC A61K9/08 A61K31/7048 

Abstract RU 2491056 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed is liquid composition of elsamitrucin for treatment of tumorour diseases or conditions, including: a) at least one stable salt of elsamitrucin, which represents product of free elsamitrucin base and organic acid and can exist as stable solid substance and does not include pseudo-salts or salts, obtained in situ, which exist only in solution, and b) pharmaceutically acceptable carrier, and claimed liquid composition does not contain antioxidants or methanol, ethanol, chloroform, n-butanol or t-butanol as admixtures, and claimed stable salt of elsamitrucin preserves at least 90% of its anti-tumor activity within 18 months in liquid form at appropriate storage temperature.

EFFECT: it is shown, that compositions, namely disclosed in claimed invention water solutions of true elsamitrucin salts, can be preserved and introduced without reduction before application.

16 cl, 7 dwg, 7 ex

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RU 2 491 056 C2

Authors

Gor Ashok

Tsang Kvok Jin

Dates

2013-08-27Published

2008-12-19Filed