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2 795 101

(13)

(51)

IPC

C07K5/02(2006-01-01)

A61K38/07(2006-01-01)

A61P35/00(2006-01-01)

A61P37/00(2006-01-01)

A61P29/00(2006-01-01)

(21) (22)

Application

2020121451, 2018-11-30

(24)

Start date

2018-11-30

(22)

Actual filing date

2018-11-30

(45)

Published

2023-04-28

(72)

Inventor

Kratz, FelixAbu Ajaj, KhalidWarnecke, AnnaNollmann, Friederike I.Koester, Stephan DavidGarcia Fernandez, JavierPes, LaraWalter, Heidi-KristinMagnusson, Johannes PallChercheja, SergheiPerez Galan, PatriciaMedda, FedericoDaum, Steffen Josef

(73)

Holder

Centurion Biopharma Corporation

ALBUMIN-BINDING PRODRUGS BASED ON AURISTATIN E DERIVATIVES Russian patent published in 2023 - IPC C07K5/02 A61K38/07 A61P35/00 A61P37/00 A61P29/00

Abstract RU 2795101 C2

FIELD: pharmaceutical industry.

SUBSTANCE: albumin-binding prodrugs derived from auristatin E, which can be used for the treatment of malignant diseases.

EFFECT: reduction in cytotoxicity compared to an equivalent dose of the unmodified active agent.

18 cl, 25 dwg, 5 ex

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RU 2 795 101 C2

Authors

Kratz, Felix

Abu Ajaj, Khalid

Warnecke, Anna

Nollmann, Friederike I.

Koester, Stephan David

Garcia Fernandez, Javier

Pes, Lara

Walter, Heidi-Kristin

Magnusson, Johannes Pall

Chercheja, Serghei

Perez Galan, Patricia

Medda, Federico

Daum, Steffen Josef

Dates

2023-04-28—Published

2018-11-30—Filed