FIELD: medicine, pharmaceutics.
SUBSTANCE: claimed invention relates to medicine and describes solid peroral drug form in form of pill, which includes: a) therapeutically effective quantity of aliskiren or its pharmaceutically acceptable salt, b) therapeutically effective quantity of hydrochlorothiazide (HCTA), and c) hydrophilic filler, which represents mixture of wheat starch and lactose. Method of obtaining solid pharmaceutical composition as well as its application are described.
EFFECT: invention ensures considerable solidity and short time of disintegration of peroral form.
28 cl, 7 ex, 8 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| HALENIC COMPOSITIONS OF ORGANIC COMPOUNDS | 2005 |
|
RU2384328C2 |
| GALENIC FORMULATIONS OF ALISKIREN | 2008 |
|
RU2483718C2 |
| GALENIC COMPOSITIONS OF ORGANIC COMPOUNDS | 2009 |
|
RU2438661C2 |
| ORAL SOLID DOSAGE FORM AND METHOD OF TREATING | 2011 |
|
RU2480210C1 |
| GALENICAL PREPARATIONS OF ORGANIC COMPOUNDS | 2010 |
|
RU2535090C2 |
| PHARMACEUTICAL COMPOSITIONS CONTAINING S1P RECEPTOR MODULATOR | 2007 |
|
RU2487703C2 |
| ADMINISTRATION OF RENIN INHIBITORS FOR PREVENTION OR TREATMENT OF DIASTOLIC DYSFUNCTION OR DIASTOLIC HEART FAILURE | 2005 |
|
RU2407523C2 |
| PHARMACEUTICAL COMPOSITION | 2006 |
|
RU2469709C2 |
| METHOD FOR PREPARING SOLID DISPERSIONS OF HIGH CRYSTALLINE THERAPEUTIC COMPOUNDS | 2007 |
|
RU2454220C2 |
| PHARMACEUTICAL COMPOSITIONS, CONTAINING IMATINIB AND RELEASE MODERATOR | 2006 |
|
RU2404775C2 |
