COMPOUNDS FOR TREATMENT OF AMYLOIDOSIS Russian patent published in 2013 - IPC A61K38/08 A61K38/10 A61P25/28 A61P25/16 

Abstract RU 2491953 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions relates to medicine and deals with application of mimotopes for treatment of β-amyloidosis, including Alzheimer's disease, where said mimotopes, are polypeptides, which contain from 4 to 20 amino-acid residues and are able to induce in vivo formation of antibodies to complete Ap 1-40/42 and short-cut from N-end forms AβpE3-40/42, Aβ3-40/42, Aβ11-40/42, AβpEl 1-40/42 and Aβ14-40/42 without impairment of physiological function of FHT.

EFFECT: group of inventions ensures reduction of risk of autoimmune diseases when introduced to subject.

29 cl, 3 ex, 4 tbl, 7 dwg

Similar patents RU2491953C2

Title Year Author Number
APPLICATION OF MIMOTOPES FOR TREATING BETA-AMYLOIDOSES 2009
  • Mandler Markus
  • Giffers Kristian
  • Mattner Frank
  • Dolishka Andrea
  • Otava Oleksandr
RU2553345C2
PEPTIDE AND METHOD OF TREATMENT OF ALZHEIMER'S DISEASE 2018
  • Morozov Aleksandr Olegovich
RU2679080C1
PEPTIDE AND METHOD OF TREATMENT OF ALZHEIMER'S DISEASE 2018
  • Morozov Aleksandr Olegovich
RU2679059C1
EPITOPE, SPECIFIC TO AMYLOID BETA OLIGOMER AND ANTIBODIES 2011
  • Keshman Nejl R.
RU2644335C2
MONOCLONAL BODY AGAINST AMYLOID BETA 2008
  • Andrea Pfajfer
  • Marija Pil'Gren
  • Andreas Mus
  • Rajan Uotts
RU2571856C2
ACTIVE IMMUNISATION FOR CREATING SOLUBLE A-BETA ANTIBODIES 2004
  • Jednok Tehd
  • Vehskez Niki
  • S'Jubert Piter A.
RU2390350C2
COMPOSITIONS OF PEPTIDE CONJUGATE AND METHODS FOR PREVENTION AND TREATMENT OF ALZHEIMER'S DISEASE 2006
  • Garski Viktor M.
  • Dzhojs Dzhozef Dzh.
  • Keller Pol M.
  • Kinni Dzhin
  • Ljan Sjaopin
  • Shiver Dzhon V.
RU2406529C2
METHOD FOR IN VITRO DIAGNOSIS OF ALZHEIMER'S DISEASE USING MONOCLONAL ANTIBODY 2006
  • Mendes Ehnrike
RU2416619C2
COPPER AGONIST THAT BINDS WITH COPPER BINDING SITE OF AMYLOID PROTEIN-PRECURSOR (APP) AND/OR EXERTS INHIBITORY EFFECT ON RELEASE OF AMYLOID Aβ-PEPTIDE 2000
  • Bejrojter Konrad
  • Mul'Tkhaup Gerd
RU2236235C2
METHOD OF TREATING ALZHEIMER'S DISEASE 2009
  • Sarasa Barrio Manuehl'
RU2526155C2

RU 2 491 953 C2

Authors

Mandler Markus

Santik Radmilla

Veninger Kharal'D

Kopinits Ehdit

Dates

2013-09-10Published

2009-06-12Filed