FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions relates to medicine and deals with application of mimotopes for treatment of β-amyloidosis, including Alzheimer's disease, where said mimotopes, are polypeptides, which contain from 4 to 20 amino-acid residues and are able to induce in vivo formation of antibodies to complete Ap 1-40/42 and short-cut from N-end forms AβpE3-40/42, Aβ3-40/42, Aβ11-40/42, AβpEl 1-40/42 and Aβ14-40/42 without impairment of physiological function of FHT.
EFFECT: group of inventions ensures reduction of risk of autoimmune diseases when introduced to subject.
29 cl, 3 ex, 4 tbl, 7 dwg
Authors
Dates
2013-09-10—Published
2009-06-12—Filed