Show metadata Hide metadata

(19)

(11)

2 492 166

(13)

(51)

IPC

C07D401/12(2006-01-01)

C07D401/14(2006-01-01)

C07D403/12(2006-01-01)

C07D403/14(2006-01-01)

C07D413/14(2006-01-01)

C07D417/12(2006-01-01)

C07D417/14(2006-01-01)

C07D487/04(2006-01-01)

A61K31/506(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2009149214/04, 2008-06-30

(24)

Start date

2008-06-30

(22)

Actual filing date

2008-06-30

(45)

Published

2013-09-10

(72)

Inventor

Chehn' VehjzhunKossrou DzhenniferFranklin LlojdGuan' BinDzhounz Dzhon KhovardKumaravel GnanasambandamLehjn BendzhaminLittke AdamLugovskoj AleksejPehn KhajzhoPauehll Noehl'Rajmundo BrajanTanaka KhirokoVesselz DzheffriUinn TomasSin' Chzhili

(73)

Holder

Sanesis Farmas'Jutikalz, Ink.Bajodzhen Ajdek Ma Ink.

COMPOUNDS SUITABLE FOR USE AS RAF KINASE INHIBITORS Russian patent published in 2013 - IPC C07D401/12 C07D401/14 C07D403/12 C07D403/14 C07D413/14 C07D417/12 C07D417/14 C07D487/04 A61K31/506 A61P35/00

Abstract RU 2492166 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a compound of formula 1:

or pharmaceutically acceptable salts thereof, where values of Cy¹; Cy²; L¹; L², R; R¹; R^x and R^y and R² are given in claim 1.

EFFECT: compounds are suitable for use as Raf protein kinase inhibitors.

36 cl, 6 tbl

Similar patents RU2492166C2

Title	Year	Author	Number
CHROMENE DERIVATIVES	2011	Alarcon Sanchez Balbino Jose Messeguer Peypoch Angel Morreale De Leon Antonio Borroto Revuelta Aldo Jorge Arellano Rojo Irene Azahara Perona Requena Almudena Carrasco Romero Esther	RU2574164C2
N-CONTAINING HETEROARYL DERIVATIVES AS JAK3 KINASE INHIBITORS	2010	Al'Mansa Rosales Karmen Salas Solana Khorte Soliva Soliva Robert Rodriges Ehskrich Serkhio Sikre Gonsales Marija Kristina	RU2553681C2
COMBINED TREATMENT OF MALIGNANT NEOPLASM USING SULPHONAMIDE COMPOUND AND IMMUNOREGULATOR	2020	Ueno, Hiroyuki Tsukioka Sayaka	RU2820817C2
HETEROARYL COMPOUNDS AND USING THEM	2009	Kljug Artur F. Petter Rassel S. Tester Richland Vehjn Tsjao Liksin Nju Detsjan Vestlin Vil'Jam Frederik Singkh Dzhasvinder Mazdijasni Khormoz	RU2536584C2
COMBINATION OF MCL-1 INHIBITOR AND TAXANE COMPOUND, THEIR APPLICATIONS AND PHARMACEUTICAL COMPOSITIONS	2018	Porter Dejl Khalilovich Ensar Shanrion Majya Marano Ana Letisiya Zhenest Olive Merino Delfin Uittl Dzhejms Vajyan Fransua Visvejder Dzhejn Lindeman Dzheffri Lessen Gijom Marangoni Elizabetta	RU2763544C2
INHIBITORS OF PROTEASE OF HEPATITIS C VIRUS AND THEIR APPLICATION	2008	Petter Rassel Singkh Dzhasvinder Kljug Artur F. Niu Dekiang K'Jao Liksin Gosh Shomir	RU2515318C2
QUINAZOLINE EFFECTIVE AS ION CHANNEL MODULATORS	2005	Uilson Din M. Termin Andreas P. Gonsales Khesus Eh. Iii Fehnning Lev T.D. N'Jubert Timoti D. Krenitski Pol Dzhoshi Pramod Kharli Dennis Dzh. Shet Urvi Bodzher Dzhoshua S.	RU2440991C2
4-AMINOQUINAZOLINE ANTAGONISTS OF SELECTIVE SODIUM AND CALCIUM ION CHANNELS	2004	Gonsales Khesus Eh. Iii Uilson Din Mitchell Termin Andreas Piter Grotenkhejs Peter Diderik Jan Chzhan Juljan' Petsoldt Bendzhamin Dzhon Fehnning Lev Tajler Devi N'Jubert Timoti Donald Tung Rodzher D. Martinboro Ehster Tsimmermann Nikole	RU2378260C2
PYRAZOLE DERIVATIVES APPLIED AS PROTEIN KINASE INHIBITORS	2001	Dehvis Robert Bebbington Dehvid Negtel Ronal'D Vehnnamehjker Marion Li Pehn Forester Kornelija Pirs Ehlbert Kehj Dehvid	RU2340611C2
AZAINDOLES, USEFUL AS INHIBITORS OF JAK AND OTHER PROTEINKINASES	2005	Salituro Franchesko Farmer Ljuk Betil Rehndi Kharrington Ehdmund Grin Dzheremi Kurt Dzhon Kam Dzhon Lauffer Dehvid Aronov Aleksandr Mikhajlovich Binch Khehjli Bojall Din Sharr'E Zhan-Dam'En Ehverit Sajmon Frajss Dam'En Mortimor Majkl P'Erar Fransuaz Robinson Dehniel Van Tszjan' Pinder Dzhoann Van Tjan'Shehn Pirs Al'Bert	RU2403252C2

RU 2 492 166 C2

Authors

Chehn' Vehjzhun

Kossrou Dzhennifer

Franklin Llojd

Guan' Bin

Dzhounz Dzhon Khovard

Kumaravel Gnanasambandam

Lehjn Bendzhamin

Littke Adam

Lugovskoj Aleksej

Pehn Khajzho

Pauehll Noehl'

Rajmundo Brajan

Tanaka Khiroko

Vesselz Dzheffri

Uinn Tomas

Sin' Chzhili

Dates

2013-09-10—Published

2008-06-30—Filed