FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to drug form, preferably, to pill for per oral application, for pain treatment with controlled release of pharmacologically active composition (A), which it contains. Drug form contains pharmacologically active composition (A), which is potential for abuse, representing opioid or opioid derivative, and hydrophilic polymer (C). Part of surface of drug form by invention is convex, and the other part of its surface is concave. Drug form has tensile strength B1, at least, 500 H in direction of tension E1 and has tensile strength B2 lower than 500 H in direction of tension E2.
EFFECT: drug form by invention is stable to rupture and stable against abuse.
16 cl, 21 dwg, 6 ex
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Authors
Dates
2013-09-27—Published
2009-01-23—Filed