METHOD OF TREATING CHRONIC FATIGUE SYNDROME Russian patent published in 2013 - IPC A61K31/13 A61K31/675 A61K31/7048 A61K31/573 A61K31/401 A61P43/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to therapy, and may be used for treating chronic fatigue syndrome. That is ensured by an integrated therapy providing the simultaneous exposure on three links of the pathological chain: excessive regulatory T cell accumulation, depletion of the hypothalamus-pituitary-adrenal axis, visceral obesity. The drug preparations used to manage the excessive regulatory T cell accumulation are intravenous alkylating preparations as follows: endoxane 800 mg/day or alkerane 10 mg/day administered every second months for three-five times; the drug preparations used to recover the hypothalamus-pituitary-adrenal axis activity is the macrolide antibiotic klacid in a single dose of 250 mg/day or prednisolone 5 mg/day administered every second day within min. 6-month therapeutic course; the drug preparation used to treat visceral obesity is the ACE inhibitor Prestarium in a single dose of 2.5 mg/day with the length of the therapeutic course being not less than one year.

EFFECT: method enables a more stable effect ensured by selective elimination of the regulatory T cells and cell growth modification, immunomodulatory and anti-inflammatory activity, protective effect on the cardiovascular system.

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