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IPC

A61K48/00(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2012102496/15, 2012-01-26

(24)

Start date

2012-01-26

(22)

Actual filing date

2012-01-26

(45)

Published

2013-08-20

(72)

Inventor

Shurdov Mikhail Arkad'EvichBogachev Sergej StanislavovichAljamkina Ekaterina Anatol'EvnaDolgova Evgenija VladimirovnaChernykh Elena RehmovnaLeplina Ol'Ga Jur'EvnaOstanin Aleksandr Anatol'EvichRogachev Vladimir AlekseevichGvozdeva Tat'Jana SergeevnaProkopenko Anastasija VadimovnaZagrebel'Nyj Stanislav NikolaevichEfremov Jaroslav Rejngol'DovichVaraksin Nikolaj Anatol'EvichRjabicheva Tat'Jana Gennad'EvnaPonomarenko Dmitrij MikhajlovichDvornichenko Viktorija VladimirovnaSidorov Sergej Vasil'EvichProskurina Anastasija SergeevnaNikolin Valerij PetrovichPopova Nelli AleksandrovnaOrishchenko Konstantin Evgen'Evich

(73)

Holder

Shurdov Mikhail Arkad'EvichBogachev Sergej StanislavovichUchrezhdenie Rossijskoj Akademii Nauk Institut Tsitologii I Genetiki Sibirskogo Otdelenija Ran So Ran)Uchrezhdenie Rossijskoj Akademii Meditsinskikh Nauk Nauchno-Issledovatel'Skij Institut Klinicheskoj Immunologii Sibirskogo Otdelenija Ramn So Ramn)Federal'Noe Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Natsional'Nyj Issledovatel'Skij Gosudarstvennyj Universitet"

METHOD OF TREATING ONCOLOGICAL DISEASES Russian patent published in 2013 - IPC A61K48/00 A61P35/00

Abstract RU 2490028 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely oncology, and may be used for the purpose of the integrated treatment of the patients with II-IV breast cancer. That is ensured by administering cytostatic preparations after the one-stage chemotherapy, including: cyclophosphan (500 mg/m²) and doxorubicin (50 mg/m²) (the schedule AC) or cyclophosphan (500 mg/m²), doxorubicin (50 mg/m²) and fluorouracil (500 mg/m²) (the schedule FAC) intravenously. Besides, the preparation Panagen in the form of gastroenteric-coated tablets 30 mg/day is regularly divided over an active period of day that makes one tablet of the preparation Panagen for six times every two hours; the administration starts on the third day following the chemotherapy. The length of the administration of the preparation Panagen is 17 days and continued until the chemotherapeutic courses according to the above schedules completed.

EFFECT: method enables the higher clinical effectiveness in breast cancer that ensures preserving and stimulating granulocyte-macrophage and lymphocyte hematopoietic lineages that makes compensation for the negative effect of leukoreducing effect of the cytostatic preparations.

1 cl, 40 dwg

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RU 2 490 028 C1

Authors

Shurdov Mikhail Arkad'Evich

Bogachev Sergej Stanislavovich

Aljamkina Ekaterina Anatol'Evna

Dolgova Evgenija Vladimirovna

Chernykh Elena Rehmovna

Leplina Ol'Ga Jur'Evna

Ostanin Aleksandr Anatol'Evich

Rogachev Vladimir Alekseevich

Gvozdeva Tat'Jana Sergeevna

Prokopenko Anastasija Vadimovna

Zagrebel'Nyj Stanislav Nikolaevich

Efremov Jaroslav Rejngol'Dovich

Varaksin Nikolaj Anatol'Evich

Rjabicheva Tat'Jana Gennad'Evna

Ponomarenko Dmitrij Mikhajlovich

Dvornichenko Viktorija Vladimirovna

Sidorov Sergej Vasil'Evich

Proskurina Anastasija Sergeevna

Nikolin Valerij Petrovich

Popova Nelli Aleksandrovna

Orishchenko Konstantin Evgen'Evich

Dates

2013-08-20—Published

2012-01-26—Filed